13 Common Medications You Should Never Mix with Alcohol

Close to 10% of the U.S. population regularly uses medications or supplements to try to fall asleep or stay asleep.7

Never use these medications when you have alcohol in your system. Sleep aids and alcohol both have sedating effects and can amplify each other.

Side effects of mixing alcohol with sleep aids may include difficulty breathing, memory problems, strange behavior, dizziness, and impaired motor control.2

Do not mix alcohol with any sleep aid, including the following:

  • Ambien (zolpidem)
  • Lunesta (eszopiclone)
  • Restoril (temazepam)
  • Unisom (doxylamine)
  • Prosom (estazolam)
  • Sominex (diphenhydramine)
  • Herbal supplements like chamomile, lavender, or valerian

6. Pain Medications

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