The concern of heart events limiting independence is real after 60, but trials like HOPE found no reduction in major cardiovascular outcomes with vitamin E. Some even noted higher heart failure risks in extensions.
Vitamin E failed to prevent events in those with diabetes or vascular disease. Practical shifts come next.
4. Bleeding Risks When Combined with Medications
Many seniors take blood thinners or aspirin, and adding high-dose vitamin E can heighten bleeding concerns through additive effects on clotting. Guidelines caution against this combination without medical oversight.
This interaction matters more with age-related changes. But exceptions exist—let’s address them
3. Limited Benefits in Specific Subgroups Only
